<b>Enamel Defects in the </b><b><i>Alpl</i></b><b><sup>- /- </sup></b><b>murine Model of Infantile Hypophosphatasia </b>
نویسندگان
چکیده
منابع مشابه
Marrow cell transplantation for infantile hypophosphatasia.
An 8-month-old girl who seemed certain to die from the infantile form of hypophosphatasia, an inborn error of metabolism characterized by deficient activity of the tissue-nonspecific isoenzyme of alkaline phosphatase (TNSALP), underwent the first trial of bone marrow cell transplantation for this heritable type of rickets. After cytoreduction, she was given T-cell-depleted, haplo-identical marr...
متن کاملBone mineralization-dependent craniosynostosis and craniofacial shape abnormalities in the mouse model of infantile hypophosphatasia.
BACKGROUND Inactivating mutations in tissue-nonspecific alkaline phosphatase (TNAP) cause hypophosphatasia (HPP), which is commonly characterized by decreased bone mineralization. Infants and mice with HPP can also develop craniosynostosis and craniofacial shape abnormalities, although the mechanism by which TNAP deficiency causes these craniofacial defects is not yet known. Manifestations of H...
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ژورنال
عنوان ژورنال: International Journal of Oral-Medical Sciences
سال: 2017
ISSN: 1347-9733,2185-4254
DOI: 10.5466/ijoms.15.126